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This effect can make a person feel full faster and longer after eating, which is part of how the medication supports weight loss

We conclude that semaglutide induces mostly mild-to-moderate and transient gastrointestinal disturbances and increases the risk of biliary disease (cholelithiasis)

[55] Inflammation and oxidative stress [edit] In metabolic conditions like obesity and diabetes, chronic inflammation and oxidative stress drive cellular damage and insulin resistance

Severe pruritus that significantly impacts quality of life or sleep, or that does not respond to conservative measures

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